8-OHDG anticorps

N° du produit ABIN7672607

Cet anticorps Lapin Polyclonal détecte spécifiquement 8-OHDG dans IHC et IF. Il présente une réactivité envers .

Aperçu rapide pour 8-OHDG anticorps (ABIN7672607)

Antigène: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 8-OHDG est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-8-OHDG anticorps

Fonction: 8-OHDG antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: KLH conjugated 8-OHdG

Isotype: IgG

Information d'application

Indications d'application: IHC: 1:50 - 1:500, IF: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.06 % PC300 and 50 % glycerol pH 7.3,

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur 8-OHDG

Antigène: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Autre désignation: 8-OHDG

Classe de substances: Chemical

Sujet:

Synonyms: 8-hydroxy-2'-deoxyguanosine|2'-Deoxy-8-oxoguanosine|7,8-Dihydro-8-oxo-2'-deoxyguanosine|8-Oxo-7,8-dihydro-2'-deoxyguanosine|8-Oxo-7,8-dihydrodeoxyguanosine|2'-Deoxy-8-oxo-D-guanosine|8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG|2'-Deoxy-8-hydroxyguanosine

Background: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.